This certainly has relevance - if nothing else, 'extreme' cooling can provide, in some cases, a performance boost that cannot be as economically accomplished with additional silicon...
For example, my planned PC buildout for this year's Permanent Fund Dividend is going to be fairly aggressively cooled - and ran at 4ghz, vs the 3.2ghz stock clock
"No can brain today. Want cheezeburger."
From NGE: Nobody Dies, by Gregg Landsman
http://www.fanfiction.net/s/5579457/1/NGE_Nobody_Dies
For example, my planned PC buildout for this year's Permanent Fund Dividend is going to be fairly aggressively cooled - and ran at 4ghz, vs the 3.2ghz stock clock
"No can brain today. Want cheezeburger."
From NGE: Nobody Dies, by Gregg Landsman
http://www.fanfiction.net/s/5579457/1/NGE_Nobody_Dies