Brexit or Breaksit?

[Matrix Dragon]

Unlikely. She is 92 years old and her main concern in the last decades has been the preservation of Royalty as a British institution (reportedly, Diana's death scandal affected so much the royals' image that it seriously made her fear it would be abolished). As such, she is keeping it together by a combination of her personal popularity and by sticking to being a ceremonial rubberstamper (she approved of Boris' proroguing of parliament within hours, without even bothering to talk to the other politicians who had asked for an audience).
So, no matter what happens in Britain she will never accept to take direct control of anything because that would make her responsible for anything that goes wrong.

And given Prince Andrew is caught up in the Epstein scandal, she has more immediate priorities than a bunch of commoners.