The big thing (in my mind) to be concerned about with the vaccines and lack of/reduced animal testing is that there is some evidence of Antibody Dependent Enhancement (ADE) in Covid, and it's definitely present in SARS and evidence for MERS as well (one of the reasons they stopped with trying to get a SARS vaccine). ADE means that if you have antibodies (either from previous exposure or a vaccine) it makes the effects of the disease worse the second time. The antibodies enhance uptake of the virus into various cells. Dengue fever is the best known for ADE effects.
COVID-19 & US healthcare system - thread relapse
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